Optogenetics
Bator F, Shekhar S, Hoerauf H, Gollisch T, van Oterendorp C, Lindner M (2026)
[Remodeling of the internal retina-Implications for targeted optogenetics].
Die Ophthalmologie 123(4): 269-275.
Optogenetics
Bator F, Shekhar S, Hoerauf H, Gollisch T, van Oterendorp C, Lindner M (2026)
[Remodeling of the internal retina-Implications for targeted optogenetics].
Die Ophthalmologie 123(4): 269-275.
Optogenetics
Rashid R, Lindner M (2026)
[Clinical endpoints and translational challenges].
Die Ophthalmologie 123(4): 276-281.
Optogenetics
Hughes S, Rodgers J, Lindner M, Peirson SN, Lucas RJ, Hankins MW (2025)
Optogenetic vision restoration in the face of secondary and tertiary remodeling in the rd1 mouse retina.
Molecular therapy : the journal of the American Society of Gene Therapy 33(11): 5840-5859.
Optogenetics
Lindner M (2025)
Perspectives and open questions in vision restoration with vMCO-010.
Molecular therapy : the journal of the American Society of Gene Therapy 33(5): 1867.
Optogenetics
Carpentiero E, Hughes S, Rodgers J, Xhaferri N, Biswas S, Gilhooley MJ, Hankins MW, Lindner M (2025)
Interaction between native and prosthetic visual responses in optogenetic visual restoration.
JCI insight 10(11).
Retinal Electrophysiology
Lindner M (2025)
The ERGtools2 package: a toolset for processing and analysing visual electrophysiology data.
Documenta ophthalmologica. Advances in ophthalmology 150(3): 169-175.
ipRGCs
Kinder L, Lindner M (2025)
Expression of Osteopontin in M2 and M4 Intrinsically Photosensitive Retinal Ganglion Cells in the Mouse Retina.
Investigative ophthalmology & visual science 66(2): 14.
Optogenetics
Rodgers J, Hughes S, Ebrahimi AS, Allen AE, Storchi R, Lindner M, Peirson SN, Badea TC, Hankins MW, Lucas RJ (2025)
Enhanced restoration of visual code after targeting ON bipolar cells compared with retinal ganglion cells with optogenetic therapy.
Molecular therapy : the journal of the American Society of Gene Therapy 33(3): 1264-1281.
Ion Channels
Renigunta V, Xhaferri N, Shaikh IG, Schlegel J, Bisen R, Sanvido I, Kalpachidou T, Kummer K, Oliver D, Leitner MG, Lindner M (2024)
A versatile functional interaction between electrically silent K subunits and K7 potassium channels.
Cellular and molecular life sciences : CMLS 81(1): 301.
AMD
Künzel SH, Broadbent E, Möller PT, Lindner M, Goerdt L, Czauderna J, Schmitz-Valckenberg S, Holz FG, Pfau M, Fleckenstein M (2024)
Association of Lesion Location and Functional Parameters with Vision-Related Quality of Life in Geographic Atrophy Secondary to Age-related Macular Degeneration.
Ophthalmology. Retina 8(8): 794-803.
Optogenetics
Rodgers J, Hughes S, Lindner M, Allen AE, Ebrahimi AS, Storchi R, Peirson SN, Lucas RJ, Hankins MW (2023)
Functional integrity of visual coding following advanced photoreceptor degeneration.
Current biology : CB 33(3): 474-486.e5.
Optogenetics
Lindner M, Gilhooley MJ, Hughes S, Hankins MW (2022)
Optogenetics for visual restoration: From proof of principle to translational challenges.
Progress in retinal and eye research 91: 101089.
Optogenetics
Gilhooley MJ, Lindner M, Palumaa T, Hughes S, Peirson SN, Hankins MW (2022)
A systematic comparison of optogenetic approaches to visual restoration.
Molecular therapy. Methods & clinical development 25: 111-123.
Optogenetics
Lindner M (2022)
The thin line between seeing risks and venturing scientific progress.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 260(8): 2773-2774.
ipRGCs
Kinder L, Palumaa T, Lindner M (2022)
[Intrinsically photosensitive retinal ganglion cells].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 119(4): 358-366.
AMD
Künzel SH, Lindner M, Sassen J, Möller PT, Goerdt L, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M, Pfau M (2021)
Association of Reading Performance in Geographic Atrophy Secondary to Age-Related Macular Degeneration With Visual Function and Structural Biomarkers.
JAMA ophthalmology 139(11): 1191-1199.
AMD
Behning C, Fleckenstein M, Pfau M, Adrion C, Goerdt L, Lindner M, Schmitz-Valckenberg S, Holz FG, Schmid M (2021)
Modeling of atrophy size trajectories: variable transformation, prediction and age-of-onset estimation.
BMC medical research methodology 21(1): 170.
Retinal Dystrophies
Birtel TH, Birtel J, Hess K, Clemens AC, Lindner M, Herrmann P, Holz FG, Gliem M (2021)
Analysis of imaging biomarkers and retinal nerve fiber layer thickness in RPGR-associated retinitis pigmentosa.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 259(12): 3597-3604.
Remodeling
Gilhooley MJ, Hickey DG, Lindner M, Palumaa T, Hughes S, Peirson SN, MacLaren RE, Hankins MW (2021)
ON-bipolar cell gene expression during retinal degeneration: Implications for optogenetic visual restoration.
Experimental eye research 207: 108553.
Optogenetics
Lindner M, Gilhooley MJ, Peirson SN, Hughes S, Hankins MW (2021)
The functional characteristics of optogenetic gene therapy for vision restoration.
Cellular and molecular life sciences : CMLS 78(4): 1597-1613.
Ion Channels
Lindner M, Gilhooley MJ, Palumaa T, Morton AJ, Hughes S, Hankins MW (2020)
Expression and Localization of Kcne2 in the Vertebrate Retina.
Investigative ophthalmology & visual science 61(3): 33.
Retinal Dystrophies
Müller PL, Pfau M, Treis T, Pascual-Camps I, Birtel J, Lindner M, Herrmann P, Holz FG (2020)
PROGRESSION OF ABCA4-RELATED RETINOPATHY: Prognostic value of demographic, functional, genetic, and imaging parameters.
Retina (Philadelphia, Pa.) 40(12): 2343-2356.
AMD
Pfau M, von der Emde L, Dysli C, Möller PT, Thiele S, Lindner M, Schmid M, Rubin DL, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2020)
Determinants of Cone and Rod Functions in Geographic Atrophy: AI-Based Structure-Function Correlation.
American journal of ophthalmology 217: 162-173.
AMD
Pfau M, Möller PT, Künzel SH, von der Emde L, Lindner M, Thiele S, Dysli C, Nadal J, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2020)
Type 1 Choroidal Neovascularization Is Associated with Reduced Localized Progression of Atrophy in Age-Related Macular Degeneration.
Ophthalmology. Retina 4(3): 238-248.
AMD
Pfau M, Müller PL, von der Emde L, Lindner M, Möller PT, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2020)
MESOPIC AND DARK-ADAPTED TWO-COLOR FUNDUS-CONTROLLED PERIMETRY IN GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION.
Retina (Philadelphia, Pa.) 40(1): 169-180.
AMD
Pfau M, von der Emde L, Dysli C, Thiele S, Möller PT, Lindner M, Nadal J, Schmid M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2019)
Light Sensitivity Within Areas of Geographic Atrophy Secondary to Age-Related Macular Degeneration.
Investigative ophthalmology & visual science 60(12): 3992-4001.
AMD
Bax NM, Valkenburg D, Lambertus S, Klevering BJ, Boon CJF, Holz FG, Cremers FPM, Fleckenstein M, Hoyng CB, Lindner M, Foveal Sparing Atrophy Study Team (FAST) (2019)
Foveal Sparing in Central Retinal Dystrophies.
Investigative ophthalmology & visual science 60(10): 3456-3467.
AMD
von der Emde L, Pfau M, Dysli C, Thiele S, Möller PT, Lindner M, Schmid M, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2019)
Artificial intelligence for morphology-based function prediction in neovascular age-related macular degeneration.
Scientific reports 9(1): 11132.
AMD
Lindner M, Pfau M, Czauderna J, Goerdt L, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2019)
Determinants of Reading Performance in Eyes with Foveal-Sparing Geographic Atrophy.
Ophthalmology. Retina 3(3): 201-210.
Retinal Dystrophies
Birtel J, Lindner M, Mishra DK, Müller PL, Hendig D, Herrmann P, Holz FG, Fleckenstein M, Gliem M, Charbel Issa P (2019)
Retinal imaging including optical coherence tomography angiography for detecting active choroidal neovascularization in pseudoxanthoma elasticum.
Clinical & experimental ophthalmology 47(2): 240-249.
AMD
Pfau M, Lindner M, Goerdt L, Thiele S, Nadal J, Schmid M, Schmitz-Valckenberg S, Sadda SR, Holz FG, Fleckenstein M, Fundus Autofluorescence in Age-Related Macular Degeneration Study Group (2019)
PROGNOSTIC VALUE OF SHAPE-DESCRIPTIVE FACTORS FOR THE PROGRESSION OF GEOGRAPHIC ATROPHY SECONDARY TO AGE-RELATED MACULAR DEGENERATION.
Retina (Philadelphia, Pa.) 39(8): 1527-1540.
Retinal Dystrophies
Müller PL, Pfau M, Möller PT, Nadal J, Schmid M, Lindner M, de Sisternes L, Stöhr H, Weber BHF, Neuhaus C, Herrmann P, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2018)
Choroidal Flow Signal in Late-Onset Stargardt Disease and Age-Related Macular Degeneration: An OCT-Angiography Study.
Investigative ophthalmology & visual science 59(4): AMD122-AMD131.
AMD
Pfau M, Lindner M, Gliem M, Steinberg JS, Thiele S, Finger RP, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2018)
Mesopic and dark-adapted two-color fundus-controlled perimetry in patients with cuticular, reticular, and soft drusen.
Eye (London, England) 32(12): 1819-1830.
AMD
Lindner M, Kosanetzky S, Pfau M, Nadal J, Gördt LA, Schmitz-Valckenberg S, Schmid M, Holz FG, Fleckenstein M, FAM-Study Group (2018)
Local Progression Kinetics of Geographic Atrophy in Age-Related Macular Degeneration Are Associated With Atrophy Border Morphology.
Investigative ophthalmology & visual science 59(4): AMD12-AMD18.
AMD
Pfau M, Lindner M, Steinberg JS, Thiele S, Brinkmann CK, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2018)
Visual field indices and patterns of visual field deficits in mesopic and dark-adapted two-colour fundus-controlled perimetry in macular diseases.
The British journal of ophthalmology 102(8): 1054-1059.
AMD
Pfau M, Lindner M, Müller PL, Birtel J, Finger RP, Harmening WM, Fleckenstein M, Holz FG, Schmitz-Valckenberg S (2017)
Effective Dynamic Range and Retest Reliability of Dark-Adapted Two-Color Fundus-Controlled Perimetry in Patients With Macular Diseases.
Investigative ophthalmology & visual science 58(6): BIO158-BIO167.
AMD
Oishi M, Oishi A, Lindner M, Pfau M, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2017)
Structural Changes in Optical Coherence Tomography Underlying Spots of Increased Autofluorescence in the Perilesional Zone of Geographic Atrophy.
Investigative ophthalmology & visual science 58(7): 3303-3310.
AMD
Pfau M, Goerdt L, Schmitz-Valckenberg S, Mauschitz MM, Mishra DK, Holz FG, Lindner M, Fleckenstein M (2017)
Green-Light Autofluorescence Versus Combined Blue-Light Autofluorescence and Near-Infrared Reflectance Imaging in Geographic Atrophy Secondary to Age-Related Macular Degeneration.
Investigative ophthalmology & visual science 58(6): BIO121-BIO130.
AMD
Lindner M, Nadal J, Mauschitz MM, Lüning A, Czauderna J, Pfau M, Schmitz-Valckenberg S, Holz FG, Schmid M, Fleckenstein M (2017)
Combined Fundus Autofluorescence and Near Infrared Reflectance as Prognostic Biomarkers for Visual Acuity in Foveal-Sparing Geographic Atrophy.
Investigative ophthalmology & visual science 58(6): BIO61-BIO67.
AMD
Lindner M, Lambertus S, Mauschitz MM, Bax NM, Kersten E, Lüning A, Nadal J, Schmitz-Valckenberg S, Schmid M, Holz FG, Hoyng CB, Fleckenstein M, Foveal sparing Atrophy Study Team (FAST) (2017)
Differential Disease Progression in Atrophic Age-Related Macular Degeneration and Late-Onset Stargardt Disease.
Investigative ophthalmology & visual science 58(2): 1001-1007.
AMD
Holz FG, Sadda SR, Staurenghi G, Lindner M, Bird AC, Blodi BA, Bottoni F, Chakravarthy U, Chew EY, Csaky K, Curcio CA, Danis R, Fleckenstein M, Freund KB, Grunwald J, Guymer R, Hoyng CB, Jaffe GJ, Liakopoulos S, Monés JM, Oishi A, Pauleikhoff D, Rosenfeld PJ, Sarraf D, Spaide RF, Tadayoni R, Tufail A, Wolf S, Schmitz-Valckenberg S, CAM group (2017)
Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration: Recommendations from Classification of Atrophy Consensus Meetings.
Ophthalmology 124(4): 464-478.
AMD
Pfau M, Lindner M, Fleckenstein M, Finger RP, Rubin GS, Harmening WM, Morales MU, Holz FG, Schmitz-Valckenberg S (2017)
Test-Retest Reliability of Scotopic and Mesopic Fundus-Controlled Perimetry Using a Modified MAIA (Macular Integrity Assessment) in Normal Eyes.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 237(1): 42-54.
AMD
Lindner M, Fang PP, Steinberg JS, Domdei N, Pfau M, Krohne TU, Schmitz-Valckenberg S, Holz FG, Fleckenstein M (2016)
OCT Angiography-Based Detection and Quantification of the Neovascular Network in Exudative AMD.
Investigative ophthalmology & visual science 57(14): 6342-6348.
Retinal Dystrophies
Lambertus S, Lindner M, Bax NM, Mauschitz MM, Nadal J, Schmid M, Schmitz-Valckenberg S, den Hollander AI, Weber BH, Holz FG, van der Wilt GJ, Fleckenstein M, Hoyng CB, Foveal sparing Atrophy Study Team (FAST) (2016)
Progression of Late-Onset Stargardt Disease.
Investigative ophthalmology & visual science 57(13): 5186-5191.
Ion Channels
Leitner MG, Michel N, Behrendt M, Dierich M, Dembla S, Wilke BU, Konrad M, Lindner M, Oberwinkler J, Oliver D (2016)
Direct modulation of TRPM4 and TRPM3 channels by the phospholipase C inhibitor U73122.
British journal of pharmacology 173(16): 2555-69.
AMD
Fleckenstein M, Grassmann F, Lindner M, Pfau M, Czauderna J, Strunz T, von Strachwitz C, Schmitz-Valckenberg S, Holz FG, Weber BH (2016)
Distinct Genetic Risk Profile of the Rapidly Progressing Diffuse-Trickling Subtype of Geographic Atrophy in Age-Related Macular Degeneration (AMD).
Investigative ophthalmology & visual science 57(6): 2463-71.
AMD
Schmitz-Valckenberg S, Nadal J, Fimmers R, Lindner M, Holz FG, Schmid M, Fleckenstein M, FAM Study Group (2016)
Modeling Visual Acuity in Geographic Atrophy Secondary to Age-Related Macular Degeneration.
Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 235(4): 215-24.
Retinal Dystrophies
Lindner M, Holz FG, Charbel Issa P (2016)
Spontaneous resolution of retinal vascular abnormalities and macular oedema in facioscapulohumeral muscular dystrophy.
Clinical & experimental ophthalmology 44(7): 627-628.
Retinal Imaging
Fang PP, Lindner M, Steinberg JS, Müller PL, Gliem M, Charbel Issa P, Krohne TU, Holz FG (2016)
[Clinical applications of OCT angiography].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 113(1): 14-22.
Retinal Imaging
Fang PP, Harmening WM, Müller PL, Lindner M, Krohne TU, Holz FG (2016)
[Technical principles of OCT angiography].
Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 113(1): 6-13.
AMD
Lindner M, Böker A, Mauschitz MM, Göbel AP, Fimmers R, Brinkmann CK, Schmitz-Valckenberg S, Schmid M, Holz FG, Fleckenstein M, Fundus Autofluorescence in Age-Related Macular Degeneration Study Group (2015)
Directional Kinetics of Geographic Atrophy Progression in Age-Related Macular Degeneration with Foveal Sparing.
Ophthalmology 122(7): 1356-65.
AMD
Lindner M, Bezatis A, Czauderna J, Becker E, Brinkmann CK, Schmitz-Valckenberg S, Fimmers R, Holz FG, Fleckenstein M (2015)
Choroidal thickness in geographic atrophy secondary to age-related macular degeneration.
Investigative ophthalmology & visual science 56(2): 875-82.
Ion Channels
Wilke BU, Lindner M, Greifenberg L, Albus A, Kronimus Y, Bünemann M, Leitner MG, Oliver D (2014)
Diacylglycerol mediates regulation of TASK potassium channels by Gq-coupled receptors.
Nature communications 5: 5540.
AMD
Grassmann F, Schoenberger PG, Brandl C, Schick T, Hasler D, Meister G, Fleckenstein M, Lindner M, Helbig H, Fauser S, Weber BH (2014)
A circulating microrna profile is associated with late-stage neovascular age-related macular degeneration.
PloS one 9(9): e107461.
AMD
Fleckenstein M, Schmitz-Valckenberg S, Lindner M, Bezatis A, Becker E, Fimmers R, Holz FG, Fundus Autofluorescence in Age-Related Macular Degeneration Study Group (2014)
The "diffuse-trickling" fundus autofluorescence phenotype in geographic atrophy.
Investigative ophthalmology & visual science 55(5): 2911-20.
Lindner M, Bertelmann T (2014)
On the ocular findings in ochronosis: a systematic review of literature.
BMC ophthalmology 14: 12.
Ion Channels
Schiekel J, Lindner M, Hetzel A, Wemhöner K, Renigunta V, Schlichthörl G, Decher N, Oliver D, Daut J (2013)
The inhibition of the potassium channel TASK-1 in rat cardiac muscle by endothelin-1 is mediated by phospholipase C.
Cardiovascular research 97(1): 97-105.
Ion Channels
Lindner M, Leitner MG, Halaszovich CR, Hammond GR, Oliver D (2011)
Probing the regulation of TASK potassium channels by PI4,5P₂ with switchable phosphoinositide phosphatases.
The Journal of physiology 589(Pt 13): 3149-62.
Ion Channels
Preprint. Xhaferri, N.; Biswas, S.; Davies, B.; Lindner, M. (2026)
Humanized Kcnv2 E151X Mouse Captures Hallmarks of KCNV2-Associated Retinal Dystrophy
bioRxiv doi: 10.64898/2026.01.05.697593
Gene Delivery
Biswas S, Carpentiero E, Xhaferri N, Streckenbach P, Renigunta V, Lindner M (2026)
Lipid nanoparticles enable mRNA delivery to diverse cell types of the inner Retina.
Molecular therapy. Nucleic acids 37(3): 102996.